Journal: Sensors (Basel, Switzerland)

Article Title: Surface Display Technology for Biosensor Applications: A Review

doi: 10.3390/s20102775

Figure Lengend Snippet: Examples of phage display-based biosensors and their performance.

Article Snippet: The performance of the SPR biosensor for detection of CRP and human IgG (hIgG) was improved by 100-fold and 10-fold through orientation control based on autodisplay technology, respectively.

Techniques: Impedance Spectroscopy, Colorimetric Assay

Journal: Scientific reports

Article Title: Novel anticancer agent, SQAP, binds to focal adhesion kinase and modulates its activity.

doi: 10.1038/srep15136

Figure Lengend Snippet: Figure 3. SPR analysis of the binding between SQAP and target proteins. Sensorgrams obtained by SPR analysis of SQAP (left) and SQP (right) with the candidate proteins: (A) SCP-2 KD 15.6 ± 2.2 μ M, (B) MFE-2 KD 14.2 ± 1.79 μ M, (C) ADRM1 KD 9.65 ± 2.91 μ M, (D) HR23B, (E) FAK KD 3.24 ± 0.21 μ M. The candidate proteins were immobilized onto the surface of a CM5 sensor chip. A solution of SQAP or SQP at variable concentrations was injected to generate result binding responses (RU) recorded as a function of time (sec). The results were analyzed using BIA evaluation 4.1.

Article Snippet: The proteins were first immobilized on a CM5 sensor chip of the SPR biosensor (Biacore 3000).

Techniques: Binding Assay, Injection

Journal: Sensors (Basel, Switzerland)

Article Title: Small Molecule Immunosensing Using Surface Plasmon Resonance

doi: 10.3390/s100807323

Figure Lengend Snippet: A summary of some SPR immunoassays of small molecules, giving the target analyte, the sample medium, reported limit of detection (LOD) and method of enhancement (if used). Note that researchers often use different methods for calculating LOD.

Article Snippet: Often, detection of drug traces on surfaces is of interest, so a SensiQ ® SPR biosensor has been applied to detection of methamphetamine traces on ceramic tiles down to 25 ng/100 cm 2 [ ].

Techniques:

Journal: Sensors (Basel, Switzerland)

Article Title: Small Molecule Immunosensing Using Surface Plasmon Resonance

doi: 10.3390/s100807323

Figure Lengend Snippet: Correlation plot for salivary cortisol samples analyzed by an SPR biosensor and by radioimmunoassay for 40 samples, from reference . Reproduced by permission of The Royal Society of Chemistry (RSC).

Article Snippet: Often, detection of drug traces on surfaces is of interest, so a SensiQ ® SPR biosensor has been applied to detection of methamphetamine traces on ceramic tiles down to 25 ng/100 cm 2 [ ].

Techniques: RIA Assay